Sodium thiosulfate 'Bulk chemical producer' and 'International Supplier' in chennai

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Sodium thiosulfate (sodium thiosulphate) is a chemical and medication. As a medication it is used to treat cyanide poisoning and pityriasis versicolor.

It is an inorganic compound with the formula Na2S2O3.xH2O. Typically it is available as the white or colorless pentahydrate, Na2S2O3·5H2O. The solid is an efflorescent (loses water readily) crystalline substance that dissolves well in water. It is also called sodium hyposulfite or "hypo".

It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system

Uses
 Sodium thiosulfate (medical use)

It is used as an antidote to cyanide poisoningThiosulfate serves as a sulfur donor for the conversion of cyanide to thiocyanate (which can then be safely excreted in the urine), catalyzed by the enzyme rhodanase. For this purpose it is used together with sodium nitrite

It has been used as treatment of calciphylaxis in hemodialysis people with end-stage kidney disease There is apparently an incompletely understood phenomenon whereby this causes severe metabolic acidosis in some patients.

In foot baths for prophylaxis of ringworm, and as a topical antifungal agent for tinea versicolor.

It is used in the management of extravasations during chemotherapy. Sodium thiosulfate prevents alkylation and tissue destruction by providing a substrate for the alkylating agents that have invaded the subcutaneous tissues. The dose may be 2 ml of 0.17 M (a solution of 4 ml 10% sodium thiosulfate and 6 ml sterile water for injection). It may be instilled subcutaneously into multiple sites using a small-gauge needle. Data are limited on this method with few recommendations.

In measuring the volume of extracellular body fluid and the renal glomerular filtration rate.

Sodium thiosulfate can be used to neutralize and ameliorate renal toxicity of the chemotherapeutic agent cisplatin This was also confirmed in clinical trials in 2018, especially in regards to reduced hearing loss

Sodium thiosulfate is also used:

As a component in hand warmers and other chemical heating pads that produce heat by exothermic crystallization of a supercooled solution.

In bacteriological water assessment, as it promotes the survival of coliform organisms by neutralizing residual chlorine
In the tanning of leather

To demonstrate the concept of supercooling in physics classes: Sodium thiosulfate, when heated, dissolves in its own water of crystallisation.
 This solution can be cooled to room temperature without recrystallisation. When crystallisation is induced by the addition of a small seed crystal, the sudden temperature rise can be experienced by touch.

As part of patina recipes for copper alloys

Often used in pharmaceutical preparations as an anionic surfactant to aid in dispersion