Potassium bromide (KBr) supplier Distributor Manufacturer in chennai Taminadu india
Potassium bromide (KBr) is a salt, widely used as an anticonvulsant and a Its action is due to the bromide ion (sodium bromide is equally effective). Potassium bromide is used as a veterinary drug, as an antiepileptic medication for dogs.
Under standard conditions, potassium bromide is a white crystalline powder. It is freely soluble in water; it is not soluble in acetonitrile. In a dilute aqueous solution, potassium bromide tastes sweet, at higher concentrations it tastes bitter, and tastes salty when the concentration is even higher. These effects are mainly due to the properties of the potassium ion—sodium bromide tastes salty at any concentration. In high concentration, potassium bromide strongly irritates the gastric mucous membrane, causing nausea and sometimes vomiting (a typical effect of all soluble potassium salts).
application
The anticonvulsant properties of potassium bromide were first noted by Sir Charles Locock at a meeting of the Royal Medical and Chirurgical Society in 1857. Bromide can be regarded as the first effective medication for epilepsy. At the time, it was commonly thought that epilepsy was caused by masturbation. Locock noted that bromide calmed sexual excitement and thought this was responsible for his success in treating seizures. In the latter half of the 19th century, potassium bromide was used for the calming of seizure and nervous disorders on an enormous scale, with the use by single hospitals being as much as several tons a year (the dose for a given person being a few grams per day). By the beginning of the 20th century the generic word had become so widely associated with being sedate that bromide came to mean a dull, sedate person or a boring platitude uttered by such a person.
Potassium bromide is used in veterinary medicine to treat epilepsy in dogs, either as first-line treatment or in addition to phenobarbital, when seizures are not adequately controlled with phenobarbital alone. Use of bromide in cats is limited because it carries a substantial risk of causing lung inflammation (pneumonitis) in them. The use of bromide as a treatment drug for animals means that veterinary medical diagnostic laboratories are able as a matter of routine to measure serum levels of bromide on order of a veterinarian, whereas human medical diagnostic labs in the US do not measure bromide as a routine test.